Sejauh ini, pencapaian terbaik Marc Marquez di MotoGP Mandalika adalah finis di posisi 3 Sprint Race MotoGP 2024. Selebihnya, dia selalu terjatuh, termasuk saat mesinnya rusak di Main Race tahun lalu.
Berikut ini adalah hasil lengkap kualifikasi MotoGP Mandalika 2025. Marco Bezzecchi raih pole position, sementara Marc Marquez berada di posisi 9.
| Posisi | Pembalap | Negara | Tim |
| 1 | Marco Bezzecchi | ITA | Aprilia Factory (RS-GP25) |
| 2 | Fermin Aldeguer | SPA | BK8 Gresini Ducati (GP24) |
| 3 | Raul Fernandez | SPA | Trackhouse Aprilia (RS-GP25) |
| 4 | Alex Rins | SPA | Monster Yamaha (YZR-M1) |
| 5 | Pedro Acosta | SPA | Red Bull KTM (RC16) |
| 6 | Luca Marini | ITA | Honda HRC Castrol (RC213V) |
| 7 | Alex Marquez | SPA | BK8 Gresini Ducati (GP24) |
| 8 | Fabio Quartararo | FRA | Monster Yamaha (YZR-M1) |
| 9 | Marc Marquez | SPA | Ducati Lenovo (GP25) |
| 10 | Miguel Oliveira | POR | Pramac Yamaha (YZR-M1) |
| 11 | Fabio Di Giannantonio | ITA | Pertamina VR46 Ducati (GP25) |
| 12 | Joan Mir | SPA | Honda HRC Castrol (RC213V) |
| 13 | Franco Morbidelli | ITA | Pertamina VR46 Ducati (GP24) |
| 14 | Jack Miller | AUS | Pramac Yamaha (YZR-M1) |
| 15 | Brad Binder | RSA | Red Bull KTM (RC16) |
| 16 | Francesco Bagnaia | ITA | Ducati Lenovo (GP25) |
| 17 | Enea Bastianini | ITA | Red Bull KTM Tech3 (RC16) |
| 18 | Johann Zarco | FRA | Castrol Honda LCR (RC213V) |
| 19 | Somkiat Chantra | THA | Idemitsu Honda LCR (RC213V) |
| 20 | Maverick Viñales | SPA | Red Bull KTM Tech3 (RC16) |